Article
Response to interferon alfa-2b therapy in mutitransfused children with beta-thalassemia and chronic hepatitis C.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Oct 1999
Spiliopoulou I, Repanti M, Katinakis S, Karana-Ginopoulou A, Papanastasiou D A
Abstract excerpt
Hepatitis C virus is responsible for the majority of cases of post-transfusion non-A non-B hepatitis in patients with thalassemia major. Interferon alfa is an effective treatment for patients with chronic hepatitis C. Response to therapy is related to the duration of treatment, the viral load in serum, and the hepatitis C virus genotype. The purpose of this study was to estimate the response of multitransfused...
Topics
- Adolescent
- Antiviral Agents
- Blood Transfusion
- Child
- Female
- Genotype
- Hepacivirus
- Hepatitis C, Chronic
- Humans
- Interferon alpha-2
- Interferon-alpha
- Male
- RNA, Viral
- Recombinant Proteins
- beta-Thalassemia