Article
Interferon treatment for chronic hepatitis C infection in hemophiliacs--influence of virus load, genotype, and liver pathology on response.
Blood - 1 Mar 1996
Hanley J P, Jarvis L M, Andrew J, Dennis R, Hayes P C, Piris J, Lee R, Simmonds P, Ludlam C A
Abstract excerpt
In this study, we assessed the effectiveness of interferon treatment in 31 hemophiliacs with chronic hepatitis C virus (HCV) infection. Interferon alfa-2a (3 MU three times weekly) was administered for 6 months. Response was assessed by both serial alanine transaminase (ALT) and HCV RNA levels measured by a sensitive semiquantitative polymerase chain reaction (PCR) method. HCV genotype was determined by...
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