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Article

Impact of sex on inheritance of ankylosing spondylitis: a cohort study.

Lancet (London, England) - 13 Nov 1999

Calin A, Brophy S, Blake D

Abstract excerpt

BACKGROUND: Ankylosing spondylitis is a genetically determined and commonly familial disorder. Men and women differ in their susceptibility to ankylosing spondylitis, with about 2.5 men affected for every woman with the disease. We investigated the influence of the sex of the index case on disease penetrance within families. METHODS: The ages at which 50% and 75% of patients were diagnosed with ankylosing...

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PMID: 10568571
DOI: 10.1016/S0140-6736(99)03219-5

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