Article
[Apparently opposite postulates of Ehrlich (Horror autotoxicus) and Metchnikoff (physiological autoimmunization) are not irreconcilable].
Bulletin de l'Academie nationale de medecine - 1 Jan 1999
Dighiero G
Abstract excerpt
In 1900, the group from Metchnikoff suggested the concept of autoimmunization by demonstrating the presence of autoantibodies in normal conditions; which was opposed to the concept of horror autotoxicus raised by Ehrlich. Landsteiner's description of the transfusion compatibility rules and 50 year-later work from Burnett's and Medawar's groups lead to the clonal deletion theory as a general explanation of...
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