Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common and diverged functions of the Drosophila gene pair D-Sp1 and buttonhead.

Mechanisms of development - 1 Dec 1999

Schöck F, Purnell B A, Wimmer E A, Jäckle H

Abstract excerpt

The Drosophila gene buttonhead (btd) is required for the formation of the mandibular, the intercalary and the antennal head segments of the embryo. The btd protein (BTD) is functionally and structurally related to the human C(2)H(2) zinc finger transcription factor Sp1. A second Sp1-like Drosophila gene, termed Drosophila Sp1 (D-Sp1), had been identified on the basis of a partial sequence showing that the gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Embryo, Nonmammalian
Share to Head
Share to Mandible

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Peripheral Nervous System

Share to Sense Organs

Share to Sp1 Transcription Factor

Share to Wings, Animal

Share to Zinc Fingers

Source

Identifiers

PMID: 10559487
DOI: 10.1016/s0925-4773(99)00215-4

Genes

BTD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common and diverged functions of the Drosophila gene pair D-Sp1 and buttonhead.PMID 10559487Read ↗

In vivo analysis of the evolutionary conserved BTD-box domain of Sp1 and Btd during Drosophila developmentSemantic proximity Read ↗

Drosophila head segmentation factor buttonhead interacts with the same TATA box-binding protein-associated factors and in vivo DNA targets as human Sp1 but executes a different biological program.Semantic proximity Read ↗

Trans- and cis-acting requirements for blastodermal expression of the head gap gene buttonhead.Semantic proximity Read ↗

The role of buttonhead and Sp1 in the development of the ventral imaginal discs of Drosophila.Semantic proximity Read ↗

Embryonic expression and characterization of a Ptx1 homolog in Drosophila.Semantic proximity Read ↗

Gene duplication, lineage-specific expansion, and subfunctionalization in the MADF-BESS family patterns the Drosophila wing hinge.Semantic proximity Read ↗

The Drosophila genes disconnected and disco-related are redundant with respect to larval head development and accumulation of mRNAs from deformed target genes.Semantic proximity Read ↗

DEAF-1 function is essential for the early embryonic development of Drosophila.Semantic proximity Read ↗

Comparative analysis of Hox downstream genes in Drosophila.Semantic proximity Read ↗

Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs.Semantic proximity Read ↗

Candidate gene screen in the red flour beetle Tribolium reveals six3 as ancient regulator of anterior median head and central complex development.Semantic proximity Read ↗

Common functions of central and posterior Hox genes for the repression of head in the trunk of Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.