Article
[Contribution of signals and antisignals in the mutational spectrum of the td-intron insertion site].
Biofizika - 1 Jan 2000
Ponomarenko M P, Ponomarenko Iu V, Kolchanov N A
Abstract excerpt
The insertion sites of the td-intron were studied. It was found that tetranucleotides W-30A-29W-28Y-27, V-19B-18W-17A-16 and A11W12A13W14 predominantly occur at normal sites (signals), and tetranucleotides Y-27W-26M-25G-24, V7B8W9A10 and Y15W16M17G18 occur more frequently at defective sites (antisignals). It was shown that antisignals make the site defective, by blocking its signals. The site becomes defective...
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