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Article

New developments in the neurobiology of the tuberous sclerosis complex

22 Oct 1999

Abstract excerpt

OBJECTIVE: To outline recent developments in the neurobiology of the tuberous sclerosis complex (TSC). BACKGROUND: TSC may be associated with neuropsychiatric disorders including epilepsy, mental retardation, and autism. The uncontrolled growth of subependymal giant cell astrocytomas may lead to hydrocephalus and death. The recent identification of mutations in two genes (TSC1 and TSC2) that cause TSC has led to...

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PMID: 10534239
DOI: 10.1212/wnl.53.7.1384

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