Familial high myopia: evidence of an autosomal dominant mode of inheritance and genetic heterogeneity.

Abstract excerpt

High myopia, defined as a refractive error inferior to -6 diopters, often appears as a familial disease. In order to precise its genetic background, we performed a segregation analysis on 32 French families (320 subjects including 120 individuals with clinical data) containing at least one high myopic person in their genealogy. Under the assumption of a two-alleles single gene model, the autosomal dominant...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alleles
• Share to Chromosome Segregation
• Share to Genes, Dominant