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Detection of Human Herpesvirus 6 by Reverse Transcription-PCR

1 Nov 1999

Abstract excerpt

The role of human herpesvirus 6 (HHV-6) in disease beyond primary infection remains unclear. We have developed and validated a new reverse transcription-PCR (RT-PCR) assay for HHV-6 that can determine the presence of HHV-6 in clinical specimens and differentiate between latent and replicating virus. Peripheral blood mononuclear cells from 109 children were evaluated for HHV-6 by RT-PCR, DNA PCR, and viral...

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PMID: 10523572
DOI: 10.1128/jcm.37.11.3672-3675.1999

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