Article
Gamma chain variants in Jamaican newborns.
Hemoglobin - 1 Jan 2000
Ahern E, Ahern V, Holder W, Palomino E, Serjeant G R, Clarke J, Brimhall B, Jones R T
Abstract excerpt
15,661 cord bloods from Jamaican infants were examined for abnormal hemoglobins using alkaline cellulose acetate electrophoresis for the initial screening, supplemented by acid agar gel electrophoresis for samples exhibiting abnormal hemoglobin bands. Of the 16 electrophoretic variants which were detected, six were fully characterized and found to be: four Hb F Port Royal (alpha2 Ggamma2 125 Glu replaced by Ala)...
Topics
- Chromatography, Gel
- Electrophoresis, Cellulose Acetate
- Female
- Fetal Hemoglobin
- Genetic Variation
- Hemoglobin A
- Hemoglobins, Abnormal
- Humans
- Infant, Newborn
- Jamaica
- Male