Transmission of a Multidrug‐ResistantMycobacterium tuberculosisStrain Resembling “Strain W” among Noninstitutionalized, Human Immunodeficiency Virus–Seronegative Patients

Abstract excerpt

Since 1990, several outbreaks of multidrug-resistant tuberculosis (MDR-TB) have been described among institutionalized patients infected with human immunodeficiency virus (HIV). We describe a community MDR-TB outbreak among HIV-seronegative patients in Cape Town, South Africa. Isolates were characterized by restriction fragment length polymorphism (RFLP) analysis and dot-blot hybridization analysis of mutations...

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