Article
Genome-wide mapping with biallelic markers in Arabidopsis thaliana.
Nature genetics - 1 Oct 1999
Cho R J, Mindrinos M, Richards D R, Sapolsky R J, Anderson M, Drenkard E, Dewdney J, Reuber T L, Stammers M, Federspiel N, Theologis A, Yang W H, Hubbell E, Au M, Chung E Y, Lashkari D, Lemieux B, Dean C, Lipshutz R J, Ausubel F M, Davis R W, Oefner P J
Abstract excerpt
Single-nucleotide polymorphisms, as well as small insertions and deletions (here referred to collectively as simple nucleotide polymorphisms, or SNPs), comprise the largest set of sequence variants in most organisms. Positional cloning based on SNPs may accelerate the identification of human disease traits and a range of biologically informative mutations. The recent application of high-density oligonucleotide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.