Article
Three per cent of Norwegian ovarian cancers are caused by BRCA1 1675delA or 1135insA.
European journal of cancer (Oxford, England : 1990) - 1 May 1999
Dørum A, Hovig E, Tropé C, Inganas M, Møller P
Abstract excerpt
Our aim was to determine the prevalence of two Norwegian BRCA1 founder mutations in ovarian cancer patients, to identify carriers and their families for medical follow-up, and to study histopathological factors. Of a cohort of 727 ovarian cancer patients, 615 gave informed consent to testing. 2.9% (18/615) of the tested patients were found to be carriers of BRCA1 1675delA (n = 13) or 1135insA (n = 5). The total...
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