[Frequency of embryonal lethality in various strains of Drosophila melanogaster under conditions of destabilization of microtubule apparatus and as affected by heat shock].

Abstract excerpt

Efficiency of heat shock and three compounds belonging to a group of mitotic poisons (colchicine (Cl), griseofulvin (Gf) and vinblastine (Vb)) in induction of dominant lethal mutations (DLM) in the Canton S wild type strain and the l(l)ts403 temperature-sensitive strain was shown. The mutagen-sensitive strain, mus(2)201Gl, displays no sensitivity to these drugs according to the DLM criterion. Heat shock followed...

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