Article
Early events in the disulfide-coupled folding of BPTI.
Protein science : a publication of the Protein Society - 1 Sept 1999
Bulaj G, Goldenberg D P
Abstract excerpt
Recent studies of the refolding of reduced bovine pancreatic trypsin inhibitor (BPTI) have shown that a previously unidentified intermediate with a single disulfide is formed much more rapidly than any other one-disulfide species. This intermediate contains a disulfide that is present in the native protein (between Cys14 and 38), but it is thermodynamically less stable than the other two intermediates with single...
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