Article
Functional complementation analysis of yeast bc1 mutants. A study of the mitochondrial import of heterologous and hybrid proteins.
European journal of biochemistry - 1 Sept 1999
van Wilpe S, Boumans H, Lobo-Hajdu G, Grivell L A, Berden J A
Abstract excerpt
Previous complementation studies with yeast bc1 mutants, defective in subunit VII or VIII, using heterologous and hybrid subunits, suggested that the requirement for import into mitochondria might significantly restrict the scope of this test for compatible proteins. Prediction algorithms indicate that the N-terminal domain of subunit VII contains all known characteristics of a mitochondrial targeting signal,...
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