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Article

Changes in the clinical phenotypes of multiple sclerosis during the past 50 years in Japan.

Journal of the neurological sciences - 15 Jun 1999

Kira J, Yamasaki K, Horiuchi I, Ohyagi Y, Taniwaki T, Kawano Y

Abstract excerpt

In order to clarify whether or not marked changes in the social environment during the past 50 years in Japan may have altered the clinical phenotypes of multiple sclerosis (MS), we retrospectively analyzed 143 consecutive patients with clinically definite MS who developed the disease between 1950 and 1997. Fifty-two patients were classified as Asian type MS showing a selective involvement of the optic nerves and...

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PMID: 10465500
DOI: 10.1016/s0022-510x(99)00115-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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