Transcription and Growth Regulatory Functions of the HIN-200 Family of Proteins

Abstract excerpt

Interferons have been shown to exert antiviral, cell growth regulatory, and immunomodulatory effects on target cells (16, 37). Both type I (α and β) and type II (γ) interferons regulate cellular activities by specifically inducing the expression or activation of endogenous proteins that perform distinct biological functions. The HIN-200 (hematopoietic interferon-inducible nuclear proteins with a 200-amino-acid...

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