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Article

The abnormal gene in X-linked lymphoproliferative syndrome.

Current opinion in immunology - 1 Aug 1999

Sullivan J L

Abstract excerpt

The gene defect responsible for X-linked lymphoproliferative syndrome, SH2D1A (SH2-domain-containing gene 1A), was recently cloned. This gene encodes a small protein of 128 amino acids containing a single SH2 domain, which is thought to play an important role in signal transduction in activated T cells. The definition of SH2D1A protein function will provide insight into the pathogenesis of fatal Epstein-Barr...

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Share to Carrier Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

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Share to Signaling Lymphocytic Activation Molecule Associated Protein

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Source

Identifiers

PMID: 10448142
DOI: 10.1016/S0952-7915(99)80072-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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