Article
Basic mechanisms of monogenic inheritance.
Epilepsia - 1 Jan 1999
Ziegler A
Abstract excerpt
To revive the appreciation of the importance of genetic studies for the understanding of neurologic diseases inherited in a monogenic fashion. After a description of the basic patterns of monogenic inheritance, the importance of linkage studies for the mapping of a disease gene is mentioned. Furthermore, the term linkage disequilibrium is introduced. Finally, several procedures used in current linkage analyses...
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