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Epstein-Barr Virus Infection of Human Astrocyte Cell Lines

1 Sept 1999

Abstract excerpt

Epstein-Barr virus (EBV) is implicated in different central nervous system syndromes. The major cellular receptor for EBV, complement receptor type 2 (CR2) (CD21), is expressed by different astrocyte cell lines and human fetal astrocytes, suggesting their susceptibility to EBV infection. We demonstrated the infection of two astrocyte cell lines, T98 and CB193, at low levels. As infection was mediated by CR2, we...

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PMID: 10438862
DOI: 10.1128/jvi.73.9.7722-7733.1999

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