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Cytomegalovirus in the Brain: In Vitro Infection of Human Brain-Derived Cells

1 Dec 1990

Abstract excerpt

Models for human cytomegalovirus (HCMV) brain infection have been developed in a variety of brain-derived cells in which the factors governing virus infectivity might be studied in vitro. Studies were initiated with brain endothelial cells, the likely portal of entry for virus into the central nervous system. Primary explant cultures of brain endothelial cells, derived from homogenates of healthy human brain,...

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PMID: 2172400
DOI: 10.1093/infdis/162.6.1252

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