Article
Inhibition of mouse mast cell proliferation and proinflammatory mediator release by benzodiazepines.
Immunopharmacology - 1 Jun 1999
Bidri M, Royer B, Averlant G, Bismuth G, Guillosson J J, Arock M
Abstract excerpt
Mast cell (MC) activation may occur in vitro and in vivo following stimulation with various immunologic or nonimmunologic agents. Such activation leads to the release of several biological mediators, including vasoactive amines, nitric oxide and cytokines, which account for the adverse effects observed during allergic reactions. While high affinity binding sites for benzodiazepines (BZDs) have been reported on...
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