Article
Familial clustering of infantile cirrhosis in Northern Germany: A clue to the etiology of idiopathic copper toxicosis.
The Journal of pediatrics - 1 Aug 1999
Müller T, Schäfer H, Rodeck B, Haupt G, Koch H, Bosse H, Welling P, Lange H, Krech R, Feist D, Mühlendahl K E, Brämswig J, Feichtinger H, Müller W
Abstract excerpt
Two cases of infantile liver cirrhosis of unknown origin occurred in a circumscribed rural area of Northern Germany. Both children had increased dietary copper exposure. The search for additional cases of what appeared to be idiopathic copper toxicosis (ICT) revealed a cluster of affected infants in this region, raising questions about the relative importance of genetic and environmental factors that are...
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