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Article

LEKTI, a Novel 15-Domain Type of Human Serine Proteinase Inhibitor

1 Jul 1999

Abstract excerpt

Proteinase inhibitors are important negative regulators of proteinase action in vivo. We have succeeded in isolating two previously unknown polypeptides (HF6478 and HF7665) from human blood filtrate that are parts of a larger precursor protein containing two typical Kazal-type serine proteinase inhibitor motifs. The entire precursor protein, as deduced from the nucleotide sequence of the cloned cDNA, exhibits 15...

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Share to Blood Coagulation and Thrombosis Mechanisms
Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
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PMID: 10419450
DOI: 10.1074/jbc.274.31.21499

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