Article
[Prion disease and brain amyloidosis].
Arkhiv patologii - 1 Jan 2000
Rukosuev V S, Zhavoronkov A A
Abstract excerpt
Human prion disorders include Kuru, Creutzfeld-Jakob disease (CJD), Gerstman-Straussler-Scheinkler syndrome (GSS), fatal familial insomnia (FFI) and prion protein cerebral amyloid angiopathy (PrPCAA). Prion diseases manifest as infections, genetic and sporadic disorders. In these diseases an abnormal form of the host's protein, prion protein protease-resistant (PrPres), is essential for pathogenic process. Host...
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