Article
Mutations in the white gene of Drosophila melanogaster affecting ABC transporters that determine eye colouration.
Biochimica et biophysica acta - 15 Jul 1999
Mackenzie S M, Brooker M R, Gill T R, Cox G B, Howells A J, Ewart G D
Abstract excerpt
The white, brown and scarlet genes of Drosophila melanogaster encode proteins which transport guanine or tryptophan (precursors of the red and brown eye colour pigments) and belong to the ABC transporter superfamily. Current models envisage that the white and brown gene products interact to form a guanine specific transporter, while white and scarlet gene products interact to form a tryptophan transporter. In...
Topics
- ATP-Binding Cassette Transporters
- Alleles
- Amino Acid Sequence
- Animals
- Drosophila Proteins
- Drosophila melanogaster
- Drug Resistance, Multiple
- Eye Proteins
- Insect Proteins
- Molecular Sequence Data
- Point Mutation
- Polymerase Chain Reaction
- Sequence Alignment