Article
Mutational analysis of the traffic ATPase (ABC) transporters involved in uptake of eye pigment precursors in Drosophila melanogaster. Implications for structure-function relationships.
The Journal of biological chemistry - 8 Apr 1994
Ewart G D, Cannell D, Cox G B, Howells A J
Abstract excerpt
The white, brown, and scarlet genes of Drosophila melanogaster encode three proteins that belong to the Traffic ATPase superfamily of transmembrane permeases and are involved in the transport of guanine and tryptophan (precursors of the red and brown eye pigments). We have determined the nucleotide sequences of two mutant white alleles (wco2 and wBwx) that cause reduced red pigmentation but have no effect on...
Topics
- Adenosine Triphosphatases
- Amino Acid Sequence
- Amino Acid Transport Systems
- Animals
- Base Sequence
- Biological Transport
- Carrier Proteins
- Codon
- DNA Primers
- Drosophila melanogaster