Emergence of heterogeneous intermediate vancomycin resistance in Staphylococcus aureus isolates in the Dusseldorf area

Abstract excerpt

J Antimicrob Chemother 1999; 43: 846–848 Sir, Hiramatsu et al.1,2,3 recently described the emergence in Japanese hospitals of heterogeneous intermediate resistance to vancomycin in clinical isolates of Staphylococcus aureus (hetero-VISA, also referred to as ‘hetero-VRSA’ ). (A hetero-VISA strain is one that is susceptible to vancomycin, i.e. MIC ≤ 4 mg/L, according to breakpoints recommended by the National...

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