Heterogeneous vancomycin-intermediate susceptibility phenotype in bloodstream methicillin-resistant Staphylococcus aureus isolates from an international cohort of patients with infective endocarditis: prevalence, genotype, and clinical significance.

doi:10.1086/606027

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Article

Heterogeneous vancomycin-intermediate susceptibility phenotype in bloodstream methicillin-resistant Staphylococcus aureus isolates from an international cohort of patients with infective endocarditis: prevalence, genotype, and clinical significance.

The Journal of infectious diseases - 1 Nov 2009

Bae In-Gyu, Federspiel Jerome J, Miró José M, Woods Christopher W, Park Lawrence, Rybak Michael J, Rude Thomas H, Bradley Suzanne, Bukovski Suzana, de la Maria Cristina Garcia, Kanj Souha S, Korman Tony M, Marco Francesc, Murdoch David R, Plesiat Patrick, Rodriguez-Creixems Marta, Reinbott Porl, Steed Lisa, Tattevin Pierre, Tripodi Marie-Françoise, Newton Karly L, Corey G Ralph, Fowler Vance G

Abstract excerpt

BACKGROUND: The significance of heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) is unknown. Using a multinational collection of isolates from methicillin-resistant S. aureus (MRSA) infective endocarditis (IE), we characterized patients with IE with and without hVISA, and we genotyped the infecting strains. METHODS: MRSA bloodstream isolates from 65 patients with definite IE from 8 countries...

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Identifiers

PMID: 19811099
DOI: 10.1086/606027
PMCID: PMC3600359

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