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Article

Frequency of CFTR gene mutations in males participating in an ICSI programme.

Human reproduction (Oxford, England) - 1 Jul 1999

Jakubiczka S, Bettecken T, Stumm M, Nickel I, Müsebeck J, Krebs P, Fischer C, Kleinstein J, Wieacker P

Abstract excerpt

A higher prevalence of cystic fibrosis transmembrane regulator (CFTR) gene mutations has been suggested both in men affected by congenital aplasia of the vas deferens, and in individuals presenting with reduced sperm quality. In this case, an increased risk for offspring being affected by cystic fibrosis (CF) can be expected in couples who are planning to undergo intracytoplasmic sperm injection (ICSI), since...

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Share to Cystic Fibrosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Fertilization in Vitro

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Source

Identifiers

PMID: 10402399
DOI: 10.1093/humrep/14.7.1833

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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