Article
Association of the MscI polymorphism of the dopamine D3 receptor gene with tardive dyskinesia in schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jul 1999
Basile V S, Masellis M, Badri F, Paterson A D, Meltzer H Y, Lieberman J A, Potkin S G, Macciardi F, Kennedy J L
Abstract excerpt
In 112 schizophrenic patients previously treated with typical neuroleptics, we investigated the putative role of the dopamine D3 receptor gene (DRD3) in tardive dyskinesia (TD). Patients were assessed for TD severity using the Abnormal Involuntary Movement Scale (AIMS) and were subsequently genotyped for the MscI polymorphism that identifies a serine to glycine substitution in DRD3. A modified analysis of...
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