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Article

Immortalization and characterization of Nijmegen Breakage syndrome fibroblasts.

Mutation research - 14 May 1999

Kraakman-van der Zwet M, Overkamp W J, Friedl A A, Klein B, Verhaegh G W, Jaspers N G, Midro A T, Eckardt-Schupp F, Lohman P H, Zdzienicka M Z

Abstract excerpt

Nijmegen Breakage Syndrome (NBS) is a very rare autosomal recessive chromosomal instability disorder characterized by microcephaly, growth retardation, immunodeficiency and a high incidence of malignancies. Cells from NBS patients are hypersensitive to ionizing radiation (IR) and display radiores...

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Identifiers

PMID: 10377945
DOI: 10.1016/s0921-8777(99)00009-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10377945-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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