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Article

Deletions causing spinal muscular atrophy do not predispose to amyotrophic lateral sclerosis.

Archives of neurology - 1 Jun 1999

Parboosingh J S, Meininger V, McKenna-Yasek D, Brown R H, Rouleau G A

Abstract excerpt

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a rapidly progressive, invariably lethal disease resulting from the premature death of motor neurons of the motor cortex, brainstem, and spinal cord. In approximately 15% of familial ALS cases, the copper/zinc superoxide dismutase gene is mutated; a juvenile form of familial ALS has been linked to chromosome 2. No cause has been identified in the remaining...

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Share to Amyotrophic Lateral Sclerosis
Share to Autoantigens
Share to Chromosomes, Human, Pair 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 5

Share to Muscular Atrophy, Spinal

Share to Polymorphism, Single-Stranded Conformational

Share to Ribonucleoproteins, Small Nuclear

Share to snRNP Core Proteins

Source

Identifiers

PMID: 10369311
DOI: 10.1001/archneur.56.6.710

Genes

NAIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Deletions causing spinal muscular atrophy do not predispose to amyotrophic lateral sclerosis.PMID 10369311Read ↗

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