Article
Bartter's syndrome in Arabic children: review of 13 cases.
Pediatrics international : official journal of the Japan Pediatric Society - 1 Jun 1999
Abdel-al Y K, Badawi M H, Yaeesh S A, Habib Y Q, al-Khuffash F A, al-Ghanim M M, al-Najidi A K
Abstract excerpt
BACKGROUND: Bartter's syndrome (BS) is an inherited disease of renal potassium wasting characterized by hypokalemic alkalosis, normal blood pressure, vascular insensitivity to pressor agents and elevated plasma concentrations of renin and aldosterone. It is caused by generalized hyperplasia of the juxtaglomerular apparatus at the site of renin production caused by mutations in the Na-K-2Cl cotransporter gene,...
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