[Bartter's syndrome and Gitelman's syndrome: Pathogenesis, pathophysiology, and therapy].

Abstract excerpt

Bartter's syndrome was reported in 1962, and Gitelman's syndrome, which is subtype of Bartter's syndrome was described later. These syndromes are characterized by hypokalemia, hypochloremic metabolic alkalosis, normal to low blood pressure, although they show hyperreninemia, and hyperaldosteronemia. The cause of these diseases have been unexplained for a long time. Recently however, from 1996 to 2002, several...

Topics

• Anion Transport Proteins
• Anti-Inflammatory Agents, Non-Steroidal
• Bartter Syndrome
• Chloride Channels
• Cholecalciferol
• Cyclooxygenase 2 Inhibitors
• Electrolytes
• Fluid Therapy
• Humans
• Membrane Proteins
• Mutation