Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Screening for mutations in the promoter and the coding region of the IGFBP1 and IGFBP3 genes in Silver-Russell syndrome patients.

Human heredity - 1 Jun 1999

Eggermann K, Wollmann H A, Tomiuk J, Ranke M B, Kaiser P, Eggermann T

Abstract excerpt

In the present study we sought to identify genetic variation in genes for insulin-like growth factor binding proteins 1 and 3 (IGFBP1, IGFBP3) in 7p12-13 which through alteration of protein function or level of expression might contribute to the manifestation of Silver-Russell syndrome. Genomic DNA samples from 49 Silver-Russell syndrome (SRS) patients and from unaffected controls were investigated by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes
Share to Germany
Share to Growth Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Insulin-Like Growth Factor Binding Protein 1

Share to Insulin-Like Growth Factor Binding Protein 3

Share to Point Mutation

Share to Polymorphism, Single-Stranded Conformational

Share to Syndrome

Source

Identifiers

PMID: 10364674
DOI: 10.1159/000022858

Genes

IGFBP1
IGFBP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Screening for mutations in the promoter and the coding region of the IGFBP1 and IGFBP3 genes in Silver-Russell syndrome patients.PMID 10364674Read ↗

Biparental expression of IGFBP1 and IGFBP3 renders their involvement in the etiology of Silver-Russell syndrome unlikely.Semantic proximity Read ↗

The endocrine phenotype in silver-russell syndrome is defined by the underlying epigenetic alteration.Semantic proximity Read ↗

New clinical and molecular insights into Silver-Russell syndrome.Semantic proximity Read ↗

Molecular characterisation of an Italian cohort of Silver-Russell Syndrome patients by -omics approachesSemantic proximity Read ↗

Frequency and clinical characteristics of distinct etiologies in patients with Silver-Russell syndrome diagnosed based on the Netchine-Harbison clinical scoring system.Semantic proximity Read ↗

Submicroscopic genomic alterations in Silver-Russell syndrome and Silver-Russell-like patients.Semantic proximity Read ↗

Molecular karyotyping as a relevant diagnostic tool in children with growth retardation with Silver-Russell features.Semantic proximity Read ↗

The Diagnostic Value of IGF-2 and the IGF/IGFBP-3 System in Silver-Russell Syndrome.Semantic proximity Read ↗

The genetic aetiology of Silver-Russell syndrome.Semantic proximity Read ↗

Searching for genomic variants in IGF2 and CDKN1C in Silver-Russell syndrome patients.Semantic proximity Read ↗

Chromosome 7p disruptions in Silver Russell syndrome: delineating an imprinted candidate gene region.Semantic proximity Read ↗

Phenotype of genetically confirmed Silver-Russell syndrome beyond childhood.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.