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Article

Localized Expression of Aromatase in Human Vascular Tissues

11 Jun 1999

Abstract excerpt

The atheroprotective effects of estrogen are well established and the presence of an estrogen receptor in vascular tissues has recently been reported. Therefore, we investigated the localization of the estrogen-producing enzyme aromatase in vascular tissues to assess the possible contribution of endocrine, paracrine, and autocrine modes of action. Aromatase was found in human vascular smooth muscle cells (SMCs)...

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PMID: 10364566
DOI: 10.1161/01.res.84.11.1285

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