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Article

Patterns of instability of expanded CAG repeats at the ERDA1 locus in general populations.

American journal of human genetics - 1 Jul 1999

Deka R, Guangyun S, Wiest J, Smelser D, Chunhua S, Zhong Y, Chakraborty R

Abstract excerpt

A highly polymorphic CAG repeat locus, ERDA1, was recently described on human chromosome 17q21.3, with alleles as large as 50-90 repeats and without any disease association in the general population. We have studied allelic distribution at this locus in five human populations and have characterized the mutational patterns by direct observation of 731 meioses. The data show that large alleles (>/=40 CAG repeats)...

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Identifiers

PMID: 10364532
DOI: 10.1086/302453
PMCID: PMC1378090

Genes

CAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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