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Article

McArdle's disease. The unsolved mystery of the reappearing enzyme.

The American journal of pathology - 1 Jun 1999

Martinuzzi A, Schievano G, Nascimbeni A, Fanin M

Abstract excerpt

We assessed the frequency of muscle fibers showing histochemical phosphorylase activity in 27 muscle biopsies from 25 unrelated patients with McArdle's disease and studied by immunohistochemistry and in situ hybridization whether the muscle-specific isoform was expressed. Positive phosphorylase fibers were observed in 19% of our series of biopsies. We show that the enzyme isoform expressed in regenerating fibers...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10362816
DOI: 10.1016/S0002-9440(10)65447-8
PMCID: PMC1866615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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