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Article

A low rate of nucleotide changes in Escherichia coli K-12 estimated from a comparison of the genome sequences between two different substrains.

FEBS letters - 30 Apr 1999

Itoh T, Okayama T, Hashimoto H, Takeda J, Davis R W, Mori H, Gojobori T

Abstract excerpt

Two genome sequences of Escherichia coli K-12 substrains, one partial W3110 and one complete MG1655, have been determined by Japanese and American genome projects, respectively. In order to estimate the rate of nucleotide changes, we directly compared 2 Mb of the nucleotide sequences from these closely-related E. coli substrains. Given that the two substrains separated about 40 years ago, the rate of nucleotide...

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Identifiers

PMID: 10350060
DOI: 10.1016/s0014-5793(99)00481-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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