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Article

Cytomegalovirus DNA detection on Guthrie cards in patients with neonatal cholestasis

1 Mar 1999

Abstract excerpt

AIM: To time the onset of cytomegalovirus (CMV) infection in patients (n = 39) with CMV associated neonatal cholestasis by analysing CMV DNA on Guthrie cards sampled at 3 days of age. METHODS: CMV infection was diagnosed by serology/urine isolation or by CMV DNA detection (polymerase chain reaction) in liver biopsy specimens. In order to time the infection dry blood filter paper discs were punched out from stored...

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PMID: 10325791
DOI: 10.1136/fn.80.2.f130

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