Article
Scavenger receptor activity is increased in macrophages from rabbits with low atherosclerotic response: studies in normocholesterolemic high and low atherosclerotic response rabbits.
Arteriosclerosis, thrombosis, and vascular biology - 1 May 1999
Teupser D, Stein O, Burkhardt R, Nebendahl K, Stein Y, Thiery J
Abstract excerpt
We have previously described 2 strains of New Zealand White rabbits with a high (HAR) or low (LAR) atherosclerotic response to hypercholesterolemia. In the present study, we focused on class A scavenger receptor (SR-A) activity and ApoE expression in macrophages from both rabbit strains. These parameters play a crucial role in maintaining cholesterol homeostasis in the arterial wall and may be involved in the...
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