Article
Limited polymorphism in the HLA-DOA gene.
Tissue antigens - 1 Apr 1999
Naruse T K, Kawata H, Anzai T, Takashige N, Kagiya M, Nose Y, Nabeya N, Isshiki G, Tatsumi N, Inoko H
Abstract excerpt
The HLA-DO molecule, a heterodimer consisting of two novel members of the class II gene family, DOA and DOB, has recently been suggested to function as an important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule. In this study, we have analyzed genetic polymorphism and allelic variation of the HLA-DOA gene in 37 HLA class II homozygous typing cells...
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