Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

No indication for APTT screening in patients on oral anticoagulant therapy.

Thrombosis and haemostasis - 1 Mar 1999

van der Meer F J, Vos H L, Rosendaal F R

Abstract excerpt

UNLABELLED: Patients on oral anticoagulant therapy (OAT) may bleed due to a very low factor IX level caused by a mutation at Ala-10 in the propeptide region of the factor IX gene. We evaluated screening of patients on OAT with an APTT to detect patients with this abnormality. In 734 patients an A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Administration, Oral
Share to Anticoagulants
Share to Factor IX

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to OAT gene

Share to Genetic Testing

Share to Hemorrhage

Share to Mutation

Share to Partial Thromboplastin Time

Source

Identifiers

PMID: 10102461

Genes

OAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10102461-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

No indication for APTT screening in patients on oral anticoagulant therapy.PMID 10102461Read ↗

Factor IX p.A37V mutation causes severe bleeding in a patient with phenprocoumon therapy.Semantic proximity Read ↗

Missense mutations at ALA-10 in the factor IX propeptide: an insignificant variant in normal life but a decisive cause of bleeding during oral anticoagulant therapy.Semantic proximity Read ↗

Abnormally short activated partial thromboplastin times are related to elevated plasma levels of TAT, F1+2, D-dimer and FVIII:C.Semantic proximity Read ↗

Routine coagulation tests are not useful as a screening tool for the FII G20210A polymorphism.Semantic proximity Read ↗

Inherited antithrombin deficiency: a review.Semantic proximity Read ↗

Thrombophilias--practical implications and testing caveats.Semantic proximity Read ↗

Genetic predisposition to bleeding during oral anticoagulant therapy: evidence for common founder mutations (FIXVal-10 and FIXThr-10) and an independent CpG hotspot mutation (FIXThr-10).Semantic proximity Read ↗

How to Capture the Bleeding Phenotype in FXI-Deficient Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.