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Article

Significant association of HLA-B and HLA-DRB1 alleles with cleft lip with or without cleft palate.

Tissue antigens - 1 Feb 1999

Sakata Y, Tokunaga K, Yonehara Y, Bannai M, Tsuchiya N, Susami T, Takato T

Abstract excerpt

Nucleotide sequence level typing of HLA-B, -DRB1, and -DPB1 alleles was performed on Japanese patients with cleft lip with or without cleft palate (CL/P). Two HLA-B alleles, B*1501 and B*5101, showed a significant positive association with CL/P. The increase of B*1501 was evident in female patients (OR=3.6, Pc=0.003), whereas the increase of B*5101 was evident in male patients (OR=3.7, Pc < 0.001). One HLA-DRB1...

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Identifiers

PMID: 10090614
DOI: 10.1034/j.1399-0039.1999.530204.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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