Article
The molecular and cellular biology of Fanconi anemia.
Current opinion in hematology - 1 Mar 1999
Garcia-Higuera I, Kuang Y, D'Andrea A D
Abstract excerpt
Fanconi anemia is a rare autosomal recessive disease characterized by multiple congenital abnormalities, bone marrow failure, and cancer susceptibility. The mean age of onset of anemia is 8 years, and the mean survival is 16 years. Death usually results from complications of bone marrow failure. Considerable progress in Fanconi anemia research has resulted from the recent identification and cloning of three...
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