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Article

Signal Transduction and Biological Function of Placenta Growth Factor in Primary Human Trophoblast1

1 Apr 1999

Abstract excerpt

Placenta growth factor (PlGF), a member of the vascular endothelial growth factor family of angiogenic factors, is prominently expressed by trophoblast. In addition to its role as a paracrine angiogenic factor within the placenta and endometrium, presence of its receptor, Flt-1, on trophoblast suggests that PlGF also may have an autocrine role(s) in regulating trophoblast function. To elucidate its role in...

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PMID: 10084962
DOI: 10.1095/biolreprod60.4.887

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