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Article

Expression of Bcl-2 by human bone marrow mast cells and its overexpression in mast cell leukemia

1 Mar 1999

Abstract excerpt

Bcl-2 protein plays a major role in the prevention of programmed cell death of differentiating cells. In the present study, the expression of cytoplasmic bcl-2 by human Bone Marrow Mast Cells (BMMC) from both normal and pathological bone marrow samples was examined. A total of 35 subjects corresponding to 9 healthy volunteers, 8 cases of adult indolent systemic mast cell disease (SMCD), 4 cases of pediatric...

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PMID: 10072109
DOI: 10.1002/(sici)1096-8652(199903)60:3<191::aid-ajh4>3.0.co;2-y

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