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Article

Quantitative Polymerase Chain Reaction for the Detection of Micrometastases in Patients With Breast Cancer

1 Mar 1999

Abstract excerpt

PURPOSE: Previous reports have indicated that reverse transcriptase polymerase chain reaction (RT-PCR) for cytokeratin 19 (CK-19) may be useful in the management of patients with breast cancer. However, the specificity of this technique is low, principally because of a high rate of false-positive results. To improve the specificity of this assay, we developed a quantitative RT-PCR methodology that enables an...

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Identifiers

PMID: 10071278
DOI: 10.1200/jco.1999.17.3.870

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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